Enantia is proud to announce the inclusion of continuous flow chemistry to our Drug Discovery and API Development services

Enantia is proud to offer flow chemistry as part of our services in medicinal chemistry and CMC development.

Flow chemistry has been a well-established technology in the petrochemical and bulk commodity industries for decades. Surprisingly, it has not been until recent years that it has gained an increasingly important role and interest in the manufacture of complex active pharmaceutical ingredients (APIs). As a result of this, it has become a powerful enabling tool, complementary to traditional batch manufacturing, for the pharmaceutical and fine chemical industries to develop more sustainable, safe, environmentally friendly and efficient chemical processes.  

Flow chemistry equipment at Enantia for CRO services in Drug Discovery and API development.

Picture: Flow reactor at Enantia

With its inclusion to our portfolio of innovative technologies, we aim to provide comprehensive services in the development of routes of synthesis, process optimization and scale up of key intermediates and API manufacturing processes. This will complement and strengthen our activities in chemistry, manufacturing, and control (CMC).

The advantages of flow chemistry enable the successful performance of processes that, otherwise, would not be feasible at industrial scale in batch reactors. For example:

  • Processes requiring accurate controlled conditions
  • Processes with hazardous reagents or intermediates
  • Processes carried out under extreme conditions of temperature or pressure
  • Photocatalytic processes

In addition, flow chemistry integrates into Enantia’s medicinal chemistry platform as an additional tool to support the company’s MedChem services.

 

 

February 12th, 2024