Solid State R&D
Screening, characterization and scale-up of polymorphs, cocrystals, salts, solvates and amorphous forms
With more than 20 years of experience in solid-state chemistry, Enantia provides expert support in the selection and development of optimal solid forms for your candidates and APIs.
Why is solid-state chemistry so important in drug development?
Because different solid forms of a pharmaceutical compound can exhibit different physical and chemical properties, like solubility and stability, directly affecting its bioavailability.
Because full understanding of the polymorphic and solvate landscape is considered a derisking strategy to control and avoid unwanted crystalline transformations during production and storage.
And because, in addition, polymorphs, salts, cocrystal, and solvates can be claimed in solid form and formulation patents to increase the intellectual protection of an API, and be used as life cycle strategy to extend market exclusivity.
Solid Form Screening and Selection
Solid Form Characterization and Pre-formulation
Crystallization Development
Purification and Chiral Resolution
Solid Form Troubleshooting
Hatch-Waxman Litigations
Equipment
At Enantia, we utilize cutting-edge instrumentation and techniques to ensure precise analysis, characterization, and optimization of chemical compounds and solid forms. Our state-of-the-art facilities and expert team enable us to provide high-quality analytical support and comprehensive solid-state research, tailored to meet the needs of your project.