Our extensive MedChem activities support the drug discovery process from initial Hit Finding, Hit-to-Lead (H2L) and Lead Optimization (LO) until Candidate selection:

• Design and synthesis of small molecules based on client-provided targets or Enantia’s proprietary ideas, as a complementary way of generating new ideas within the project.
• Application of rational drug design or knowledge-based approaches to tailor compounds for therapeutic success.
• Rapid modifications driven by biological and ADMET screening feedback to enhance potency, selectivity, and drug-like properties.
• Parallel synthesis and automated purification techniques, including preparative HPLC, enable rapid development of focused libraries.
• Convergent synthesis strategies introduce diversity points late in the sequence, ensuring streamlined workflows.